Clenbuterol im Bodybuilding – allgemeine Informationen über das Sympathomimetikum
Clenbuterol is not an anabolic steroid, but a stimulant from the group of sympathomimetics. This family includes compounds well known to most people, including caffeine, ephedrine, albuterol, amphetamines, cocaine, and many others. This is a really big group of drugs that are all related to each other. All stimulants are similar to each other and work in the same way. Clenbuterol’s action on the nervous system is due to its interaction with the adrenoceptors in the various tissues and cells of the body. Due to Clenbuterol’s affinity for these receptors, various effects occur, the nature of which depends on the type of tissue stimulated. Particular attention is paid to the role of clenbuterol in adipose tissue.
There are two main types of
Adrenoreceptors in the body: alpha and beta receptors. Within these two different types there are 9 subtypes namely Alpha-1, Alpha-2, Beta-1, Beta-2 etc. Clenbuterol and other stimulants differ in their ability to stimulate the different receptor subtypes. Clenbuterol has a strong selective stimulating effect on beta-2 adrenoceptors and is therefore known as a beta-2 receptor agonist. Clenbuterol ‘s action on beta-2 adrenoceptors triggers fat breakdown with the release of free fatty acids (lipolysis). This has made it popular with bodybuilders and athletes, but also with celebrities and anyone else who wants to lose weight.
The use of Clenbuterol
In medicine, Clenbuterol is used to treat bronchial asthma as a bronchodilator. It can be used in inhaled form to relieve asthma attacks. Clenbuterol is typically used for asthma therapy in European countries, while Albuterol, a compound closely related to Clenbuterol, is commonly prescribed for this purpose in North America. The stimulation of the beta-2 receptors in the bronchi by the drug leads to an expansion of the bronchi (airway widening). The receptors in the lungs, throat and nasal mucosa are also affected. Almost every sympathomimetic has this effect, but clenbuterol and albuterol are the most effective in this regard and are therefore used to relieve asthma attacks. Clenbuterol used to have other medical indications:
Clenbuterol acts primarily on beta-2 receptors, but also stimulates other receptor subtypes, albeit to a lesser extent. In comparison, ephedrine activates the beta and alpha receptors to about the same extent as clenbuterol, which primarily stimulates one receptor subtype. Clenbuterol is well known in the bodybuilding community for its anabolic effects on muscle tissue. But in fact, it has a minimal anabolic effect, which was found mainly in animals and to a lesser extent in humans (therefore, in order to get a significant effect, the drug should be used for a long time).
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Side Effects of Clenbuterol
Since Clenbuterol is not an anabolic steroid, it does not have any of the side effects normally associated with this group of drugs. However, Clenbuterol has side effects common to all compounds from the stimulant class. Therefore, many of the unwanted effects of Clenbuterol are more or less the same as those of caffeine, ephedrine, and other stimulants. Clenbuterol use can also produce unique side effects not common to other compounds from the stimulant family.
One such unique unwanted reaction commonly caused by Clenbuterol use is muscle spasms. A similar side effect is observed with the related drug albuterol. The reason for this is the depletion of the amino acid taurine in the body caused by clenbuterol. Studies have confirmed that taking Clenbuterol leads to a reduction in taurine levels in muscle and blood plasma. Like magnesium, potassium, and sodium, this amino acid is important for regulating nerve impulses and signals that control contraction and relaxation of all muscle types. A lack of taurine can lead to involuntary, often intense and painful muscle contractions that lead to cramps. Taurine supplementation with a daily dose of 2,
